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Reports of research progress

2017

  1. The low hSOD1 transgene copy number mice as an animal model dedicated to cell replacement strategies  Majchrzak M, Stanaszek L, Walczak P, Janowski M, Lukomska B, Berlin Brain and BRAIN PET 28th Symposium on Cerebral Blood Flow, Metabolism and Function and 13th Conference on Quantification of Brain Function with PET 1-4 April 2017, Berlin, Germany (poster)
  2. Global glia replacement as a strategy for treatment of amyotrophic lateral sclerosis – a basic study on experimental mice model  Stanaszek L, Majchrzak M, Sanford J, Walczak P, Lukomska B, Janowski M. Berlin Brain and BRAIN PET 28th Symposium on Cerebral Blood Flow, Metabolism and Function and 13th Conference on Quantification of Brain Function with PET 1-4 April 2017, Berlin, Germany (poster)

2016

  1. SOD1/Rag2 mice with low copy number of the SOD1 gene as a model for stem cell therapy of ALS  Stanaszek L, Majchrzak M, Jablonska A, Rogers O, Sajja S, Lukomska B, Walczak P, Janowski M, European Network for the Cure of ALS Meeting 2016, 19-21.05.2016, Mediolan, Italy, (poster)
  2. In search for optimal source of glial progenitors for clinical applications  Majchrzak M, Stanaszek L, Sanford J, Janowski M, Walczak P, Lukomska B, Stop ALS: Therapeutic Targets, Animal Models, Stem Cells and Clinical Applications, 22-23.06.2016, Olsztyn (oral presentation)
  3. Transplantation of grp cells in sod1/rag2 mice  Stanaszek L, Majchrzak M, Jablonska A, Rogers O, Sajja S, Lukomska B, Walczak P, Janowski M . Stop ALS: Therapeutic Targets, Animal Models, Stem Cells and Clinical Applications, 22-23.06.2016, Olsztyn, (oral presentation)
  4. Glial restricted progenitor transplantation as a novel therapeutic approach in amyotrophic lateral sclerosis (ALS)  Majchrzak M, Stanaszek L, Janowski M, Walczak P, Lukomska B, 3rd International Spinal Cord Injury and Neurotrauma Summer School 27.06-1.07.2016, Hattingen, Germany (poster)
  5. Characterization of mice and canine glial restricted precursor cells as the potential tools for cell-based therapy in experimental models of amyotrophic lateral sclerosis  Majchrzak M, Stanaszek L, Sanford J, Walczak P, Janowski M, Lukomska B 7th Annual Conference on Stem Cell and Regenerative medicine, 4-5.08.2016, Manchester, Great Britain (poster)
  6. The potential therapeutic effect of canine glial restricted precursors transplanted in demyelinated mice model  Majchrzak M, Stanaszek L, Sanford J, Walczak P, Janowski M, Lukomska B  TERM STEM 2016 and NanoTech4ALS Meeting 27-28 October 2016, Guimarães, Portugal, (oral presentation)
  7. A variable hSOD1 copy number in immunodeficient mouse as a versatile model of amyotrophic lateral sclerosis for stem cell therapy.  Stanaszek L, Majchrzak M, Lukomska B, Walczak P, Janowski M:  TERM STEM 2016 and NanoTech4ALS Meeting 27-28 October 2016, Guimarães, Portugal, (oral presentation).
  8. Możliwość wykorzystania terapii komórkowej w leczeniu mielopatii zwyrodnieniowej u psów, Majówka Neurologiczna,  Joanna Sanford,  Wrocław (oral presentation)
  9. Joanna Sanford, XV Konferencja PTNW Stop ALS: Therapeutic target, Animal models, Stem cells and clinical applications , Olsztyn (oral presentation)
  10. Joanna Sanford, konnferencja Hill’s :Metody medycyny regeneracyjnej w dermatologii weterynaryjnej, SGGW Warszawa (oral presentation)
  11. Assessment of Immunological Properties of Glial Restricted Progenitors for Potential Application in ALS Therapy.  Urszula Kozlowska, Aleksandra Klimczak, Maciej Kurpisz Workshop : Stop ALS: Therapeutic Targets, Animal Models, Stem Cells and Clinical Applications. Olsztyn, Poland, 22-23 June, 2016 (oral presentation)
  12. Urszula Kozłowska, Aleksandra Klimczak, Maciej Kurpisz: Immunological and Biological Properties of Glial Restricted Progenitors for Potential Application in ALS Therapy. Połączone konferencje:  The 13th International Symposium "Molecular basis of pathology and therapy in neurological disorders” and “The 4th Interneational Conference, Stem cells: therapeutic outlook for central nervous system disorder”. Warsaw, November 17-18, 2016 .Abstrakt opubl. Folia Neuropathol. 2016, Vol. 54(3), str. 340 (oral presentation)
  13. Urszula Kozłowska, Aleksandra Klimczak, Maciej Kurpisz, Graft Immunoprotection Concepts for Prospect Cellular Therapy of Neurodegenerative Diseases, Institute of Human Genetics, PAS Poznań, 31.05.2016 (oral presentation)
  14. Aleksandra Klimczak.  Immunological Aspects Related to Transplantation of Cells and Tissues. Workshop: Stop ALS: Therapeutic Targets, Animal Models, Stem Cells and Clinical Applications. Olsztyn, Poland, 22-23 June, 2016 (oral presentation)
  15. Real Time MRI-guided convection-enhanced delivery of gliotoxin in pig brain to induce focal demyelination as a model of multiple sclerosis Kalkowski L, Malysz-Cymborska I., Golubczyk D., Janowski M., Holak P., Milewska K., Adamiak Z., Wojtkiewicz J., Maksymowicz W., Kedziorek D., Walczak P., World Molecular Imaging Congress, New York, 2016 (oral presentation)
  16.  MRI Guided Intracerebral Convection-Enhanced Injection of Gliotoxin to Model Focal Demyelination in Pigs Lukasz Kalkowski, Izabela Malysz-Cymborska, Dominika Golubczyk, Miroslaw Janowski, Piotr Holak, Kamila Milewska, Zbigniew Adamiak, Joanna Wojtkiewicz, Wojciech Maksymowicz, Dorota Kedziorek and Piotr Walczak,  Interventional MRI Symposium, Baltimore, 2016 (oral presentation)
  17. Canine degenerative myelopathy as unique model of human amyotrophic lateral sclerosis Dominika Golubczyk, Izabela Malysz – Cymborska, Lukasz Kalkowski, Miroslaw Janowski, Joanna Sanford, Joan R Coates, Joanna Wojtkiewicz, Wojciech Maksymowicz, Piotr Walczak, TERMSTEM 2016,  Portugal, 2016 (oral presentation)
  18. Optimization of injectable hydrogels to support survival and facilitate migration of embedded progenitor cells Izabela Malysz – Cymborska, Dominika Golubczyk, Lukasz Kalkowski, Miroslaw Janowski, Joanna Wojtkiewicz, Wojciech Maksymowicz, Piotr Walczak, TERMSTEM 2016, Portugal, 2016 (oral presentation)
  19. Migration and survival of glial restricted precursors grown as single cells or neurospheres embedded in hyaluronic acid- based hydrogels with the prospect of using them as intrathecally injectable composites, Malysz-Cymborska I, Kalkowski L, Golubczyk D, Janowski M, Wojtkiewicz J, Walczak P., Leipzig, 2016 (poster)
  20. Improving efficacy of intrathecal targeting of cells by the use of injectable hydrogels,  Malysz-Cymborska I, Golubczyk D,  Kalkowski L, Janowski M, Wojtkiewicz J,  Maksymowicz W , Walczak P,  Workshop: Stop ALS: Therapeutic Targets, Animal Models, Stem Cells and Clinical Applications. Olsztyn, Poland, 22-23 June, 2016 (oral presentation)
  21. The role of glia in canine degenerative myelopathy  Golubczyk D, Malysz-Cymborska I,  Kalkowski L, Janowski M, Sanford J, Coates J, Wojtkiewicz J , Walczak P,  Workshop: Stop ALS: Therapeutic Targets, Animal Models, Stem Cells and Clinical Applications. Olsztyn, Poland, 22-23 June, 2016 (oral presentation)
  22. Convection enhanced delivery  Kalkowski L, Golubczyk D, Malysz-Cymborska I,  , Janowski M, Sanford J, Coates J, Wojtkiewicz J , Walczak P,  Workshop: Stop ALS: Therapeutic Targets, Animal Models, Stem Cells and Clinical Applications. Olsztyn, Poland, 22-23 June, 2016 (oral presentation)